PubChem Property API

Power User Gateway (PUG) REST API for accessing PubChem chemical compound data including properties, synonyms, descriptions, and identifiers. Supports various input types including CID, name, SMILES, and InChIKey.

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Base URL: https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/
Auth: unknown
Endpoints: 13
Reachable: yes
CORS: unknown
Last checked: 2026-03-14 16:09:20.346112

Links

Homepage: https://pubchem.ncbi.nlm.nih.gov/
API Base: https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/

100.0%

Uptime (7d)

518ms

Avg latency (7d)

8

Probes (7d)

Latency (7d)

Success Rate (7d)

Topics

CHEMISTRY, GOVERNMENT, SCIENCE

Endpoints

Method Path Summary Auth Last Status Latency
GET /compound/cid/{cid}/description/JSON Get compound descriptions by CID — — —
GET /compound/cid/{cid}/property/{properties}/{output} Get compound properties by CID — 200 397ms
GET /compound/cid/{cid}/property/{property}/JSON Get compound properties by CID — — —
GET /compound/cid/{cid}/synonyms/JSON Get compound synonyms by CID — — —
GET /compound/inchikey/{inchikey}/cids/JSON Get CIDs by InChIKey — — —
GET /compound/inchikey/{inchikey}/property/{properties}/{output} Get compound properties by InChIKey — 200 450ms
GET /compound/inchikey/{inchikey}/property/{property}/JSON Get compound properties by InChIKey — — —
GET /compound/name/{name}/cids/JSON Get CIDs by compound name — — —
GET /compound/name/{name}/description/JSON Get compound descriptions by name — — —
GET /compound/name/{name}/property/{properties}/{output} Get compound properties by name — 200 481ms
GET /compound/name/{name}/property/{property}/JSON Get compound properties by name — — —
GET /compound/name/{name}/synonyms/JSON Get compound synonyms by name — — —
GET /compound/smiles/{smiles}/property/{properties}/{output} Get compound properties by SMILES — 200 772ms