{output}: Get compound properties by SMILES

API: nih.gov:pubchem-property-api
Endpoint: /compound/smiles/{smiles}/property/{properties}/{output}
Response format: application/json
Auth: unknown
Method: GET
Last Status: 200
Latency: 831ms

Description

Retrieve chemical properties for a compound specified by its SMILES notation

Parameters (3)

output (string, path, required, default: JSON)

Output format

Constraints: {'enum': ['JSON', 'XML']}

properties (string, path, required)

Comma-separated list of properties to retrieve

smiles (string, path, required)

SMILES string (URL-encoded if necessary)

Examples (3)

Get properties by SMILES openapi-spec

curl 'https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/CC(=O)Oc1ccccc1C(=O)O/property/MolecularFormula/JSON'

import requests

resp = requests.get("https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/CC(=O)Oc1ccccc1C(=O)O/property/MolecularFormula/JSON")
data = resp.json()

import zingu_apis

api = zingu_apis.api("pubchem-property")
result = api.fetch("compound/smiles/{smiles}/property/{properties}/{output}")

for item in result:
    print(item)

const resp = await fetch("https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/CC(=O)Oc1ccccc1C(=O)O/property/MolecularFormula/JSON");
const data = await resp.json();

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Auto Table Raw

Get compound properties by SMILES openapi-spec

curl 'https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/C1CCCCC1/property/MolecularFormula,MolecularWeight/{output}'

import requests

resp = requests.get("https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/C1CCCCC1/property/MolecularFormula,MolecularWeight/{output}")
data = resp.json()

import zingu_apis

api = zingu_apis.api("pubchem-property")
result = api.fetch("compound/smiles/{smiles}/property/{properties}/{output}")

for item in result:
    print(item)

const resp = await fetch("https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/C1CCCCC1/property/MolecularFormula,MolecularWeight/{output}");
const data = await resp.json();

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Auto Table Raw

Get compound properties by SMILES probe-gate

curl 'https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/C1CCCCC1/property/MolecularFormula,MolecularWeight/JSON'

import requests

resp = requests.get("https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/C1CCCCC1/property/MolecularFormula,MolecularWeight/JSON")
data = resp.json()

import zingu_apis

api = zingu_apis.api("pubchem-property")
result = api.fetch("compound/smiles/{smiles}/property/{properties}/{output}")

for item in result:
    print(item)

const resp = await fetch("https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/C1CCCCC1/property/MolecularFormula,MolecularWeight/JSON");
const data = await resp.json();

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Auto Table Raw

Probe History

Latency

Status Codes

Time	Status	Latency
2026-04-16 01:58:57.952692	200	831ms
2026-04-16 01:50:58.299153	200	669ms
2026-04-15 02:03:43.940550	200	852ms
2026-04-15 00:33:36.518452	200	692ms
2026-04-14 03:10:31.270738	200	789ms
2026-04-14 03:01:18.368335	200	925ms
2026-04-12 14:32:14.026545	200	718ms
2026-04-12 13:23:17.266487	200	799ms
2026-04-10 04:32:43.452289	200	787ms
2026-04-10 00:39:24.865797	200	804ms
2026-04-09 01:42:17.982412	200	651ms
2026-04-09 00:44:01.143499	200	674ms
2026-03-23 09:39:33.476327	200	772ms
2026-03-23 09:22:04.178633	200	649ms