GET /homology/id/{species}/{id}Get orthologous and paralogous genes for a specific gene in a specific species. Returns homologous genes with their locations, percent identity, and alignment coverage. This is the primary endpoint for orthology lookup - use it to find the mouse ortholog of a human gene, or paralogs within a species. The `type` parameter lets you filter for orthologs, paralogs, or projection spanned homologs.
Retrieves homology information (orthologs) by species and Ensembl gene ID.
- Default returns all homologies including distant orthologs - filter by type for cleaner results - Each homology includes `source` and `target` percent identity and alignment coverage - Use `type=orthologues` to get only cross-species orthologs - Use `type=paralogues` to get only within-species paralogs - The `method_link_type` tells you how the homology was inferred (e.g., ENSEMBL_ORTHOLOGUES)
(string, path, required)
Ensembl gene ID
(string, path, required)
Species name (e.g., human)
(string, query, optional)
Species to search for homologs in
(string, query, optional, default: all)
Type of homology
Constraints: {'enum': ['orthologues', 'paralogues', 'projections', 'all']}
| Title | Type | URL | Action |
|---|---|---|---|
| Get orthologous genes for BRCA2 in mouse | probe-gate |
https://rest.ensembl.org/homology/id/homo_sapiens/ENSG00000139618?type=orthologues&target_species=mouse&content-type=application/json |
No probe data for this endpoint yet.