ChEMBL API

ChEMBL is a manually curated database of bioactive molecules with drug-like properties. It brings together chemical, bioactivity and genomic data to aid the translation of genomic information into effective new drugs. This API provides access to data on compounds, targets, assays, activities, drugs, and mechanisms of action.

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Base URL: https://www.ebi.ac.uk/chembl/api/data/
Auth: none
Endpoints: 59
Reachable: yes
CORS: unknown
Last checked: 2026-03-14 16:08:08.931254

Links

Homepage: https://www.ebi.ac.uk/chembl
API Base: https://www.ebi.ac.uk/chembl/api/data/
SDKs:

100.0%

Uptime (7d)

724ms

Avg latency (7d)

62

Probes (7d)

Latency (7d)

Success Rate (7d)

Endpoints

Method Path Summary Auth Last Status Latency
GET /activity Search bioactivities — 200 442ms
GET /activity.json List activities — — —
GET /activity/search Search activities — 200 952ms
GET /activity/search.json Search activities — — —
GET /activity/{activityId} Get activity by ID — 404 448ms
GET /activity/{activity_id} Get activity by ID — — —
GET /activity/{activity_id}.json Get activity details — — —
GET /assay List assays — 200 294ms
GET /assay.json List assays — — —
GET /assay/search Search assays — — —
GET /assay/search.json Search assays — — —
GET /assay/{assayId} Get assay by ID — 200 158ms
GET /assay/{assay_chembl_id} Get assay by ID — — —
GET /assay/{chembl_id}.json Get assay details — — —
GET /chembl_id_lookup/search Search ChEMBL IDs — 200 146ms
GET /chembl_id_lookup/{chemblId} Lookup ChEMBL ID — 200 175ms
GET /chembl_id_lookup/{chembl_id} Lookup ChEMBL ID — — —
GET /chembl_id_lookup/{chembl_id}.json Lookup ChEMBL ID — — —
GET /document List documents — 200 202ms
GET /document.json List documents — — —
GET /document/search.json Search documents — — —
GET /document/{chembl_id}.json Get document details — — —
GET /document/{documentId} Get document by ID — 404 176ms
GET /drug List approved drugs — 200 829ms
GET /drug.json List drugs — — —
GET /drug/{chembl_id}.json Get drug details — — —
GET /image/{chemblId} Get molecule image — 200 171ms
GET /image/{chembl_id}.svg Get molecule image — — —
GET /image/{molecule_chembl_id} Get molecule image — — —
GET /mechanism Get drug mechanisms — — —
GET /mechanism.json List mechanisms — — —
GET /mechanism/{mec_id}.json Get mechanism details — — —
GET /molecule Search molecules — 200 742ms
GET /molecule.json List molecules — 200 644ms
GET /molecule/search Search molecules — 200 298ms
GET /molecule/search.json Search molecules — — —
GET /molecule/set/{chembl_ids}.json Get multiple molecules — — —
GET /molecule/set/{ids} Get multiple molecules — 200 348ms
GET /molecule/set/{molecule_chembl_ids} Get multiple molecules by IDs — — —
GET /molecule/{chemblId} Get molecule by ChEMBL ID — 200 278ms
GET /molecule/{chembl_id} Get molecule by ChEMBL ID — 200 210ms
GET /molecule/{chembl_id}.json Get molecule details — — —
GET /molecule/{molecule_chembl_id} Get molecule by ID — — —
GET /similarity/{smiles}/{similarity} Similarity search — 200 523ms
GET /similarity/{smiles}/{similarity}.json Similarity search — — —
GET /status API status — — —
GET /status.json Get API status — 200 2130ms
GET /substructure/{smiles} Substructure search — 200 2636ms
GET /substructure/{smiles}.json Substructure search — — —
GET /target Search targets — 200 1775ms
GET /target.json List targets — 200 2623ms
GET /target/search Search targets — 200 2074ms
GET /target/search.json Search targets — — —
GET /target/set/{chembl_ids}.json Get multiple targets — — —
GET /target/set/{ids} Get multiple targets — 200 808ms
GET /target/{chemblId} Get target by ChEMBL ID — 200 164ms
GET /target/{chembl_id} Get target by ChEMBL ID — 200 529ms
GET /target/{chembl_id}.json Get target details — — —
GET /target/{target_chembl_id} Get target by ID — — —